In familial hemiplegic migraine, the underlying mutation in a calcium channel causes:

In familial hemiplegic migraine, the underlying mutation in a calcium channel causes:

In familial hemiplegic migraine, the underlying mutation in a calcium channel causes:





  1. abnormally functioning pain receptors in the peripheral nervous system.
  2. enhanced synaptic excitation of second-order pain-sensitive neurons.
  3. abnormal activation of thalamic pain centers.
  4. abnormal activation of neocortical pain centers.
  5. the syndrome by some unknown mechanism.

Answer: 5