The differential release of small, clear vesicles, versus large, dense-core vesicles, is best explained by:

The differential release of small, clear vesicles, versus large, dense-core vesicles, is best explained by:

The differential release of small, clear vesicles, versus large, dense-core vesicles, is best explained by:





  1. biophysical differences in the vesicles' lipids that allow for easier fusion of small vesicles.
  2. a more sensitive calcium-release mechanism on the dense-core vesicles.
  3. a more delocalized calcium signal generated by intense neural stimulation.
  4. the presence of novel fusion proteins on the dense core vesicles that bind neuropeptides.
  5. All of the above


Answer: 3