The key aspect of receptor gating in the associative induction of hippocampal LTP is that:

The key aspect of receptor gating in the associative induction of hippocampal LTP is that:

The key aspect of receptor gating in the associative induction of hippocampal LTP is that:



  1. all glutamate receptors open automatically whenever glutamate is in the synaptic cleft.
  2. the NMDA receptor acts as a molecular coincidence detector.
  3. the AMPA receptor allows calcium into the cell only after the NMDA receptor is activated.
  4. both the NMDA and AMPA channels must be open in order for the cell to depolarize.
  5. All of the above are key aspects of LTP induction.

Answer: 2