To date, which of the following is not part of the experimental evidence favoring the vesicular release hypothesis of neurotransmission?

To date, which of the following is not part of the experimental evidence favoring the vesicular release hypothesis of neurotransmission?

To date, which of the following is not part of the experimental evidence favoring the vesicular release hypothesis of neurotransmission?



  1. Fixed size of MEPPs
  2. Quantized distribution of events occurring at the neuromuscular junction
  3. Visualization of synaptic vesicles using electron microscopy
  4. Correspondence between a vesicle's acetylcholine content and MEPP size
  5. Visualization of acetylcholine molecules diffusing out of the neck of the membrane-fused vesicle

Answer: 5