Which of the following is a major advantage to researchers of the Xenopus oocyte expression system?

Which of the following is a major advantage to researchers of the Xenopus oocyte expression system?

Which of the following is a major advantage to researchers of the Xenopus oocyte expression system?



  1. Xenopus is the only lower vertebrate whose genome has been sequenced.
  2. The unusually small size of the eggs makes patch-clamping relatively easy.
  3. The oocytes have many endogenous ion channels to which exogenous channels can be compared.
  4. The oocytes have quite thin membranes, which amplifies the ionic currents.
  5. It facilitates physiological characterization of modified ion channel genes.

Answer: 5