Which of the following is not true for G protein-coupled receptors (GPCRs)?

Which of the following is not true for G protein-coupled receptors (GPCRs)?


A) Agonists mimic the effect of the natural ligand.
B) Antagonists block the normal effect of the natural ligand.
C) GPCRs interact with heterodimeric G proteins.
D) GPCRs are have seven transmembrane helices.
E) There exist >100 orphan GPCRs in the human genome with no known ligand.

Answer: C


Biology

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