Which of the following mechanisms contributes to the long-term enhancement of the gill withdrawal reflex in Aplysia but is not involved in the short-term enhancement of the reflex?

Which of the following mechanisms contributes to the long-term enhancement of the gill withdrawal reflex in Aplysia but is not involved in the short-term enhancement of the reflex?





  1. Activation of G-protein-coupled receptors by serotonin
  2. Phosphorylation of CREB
  3. Activation of adenylyl cyclase
  4. Activation of protein kinase A
  5. Decreased opening of potassium channels during presynaptic action potentials

Answer: 2