Which statement about the mechanisms underlying hippocampal LTP induction is false?

Which statement about the mechanisms underlying hippocampal LTP induction is false?





  1. An influx of calcium triggers two or more intracellular processes in the postsynaptic dendritic spine.
  2. Calcium may trigger the release of a retrograde messenger that enhances transmitter release from the presynaptic terminal.
  3. Calcium may activate CaM kinase II in such a way that it switches to a long-term "on" state.
  4. Calcium may activate a signaling cascade that causes the insertion of glutamate receptors into the postsynaptic membrane.
  5. Calcium decreases a resting leak current of sodium so that the postsynaptic cell is closer to threshold and therefore fires more easily.

Answer: 5