If a cell has 8 chromosomes at metaphase of mitosis, how many chromosomes will it have during anaphase? DNA and RNA If a cell has 8 chromosomes at metaphase of mitosis, how many chromosomes will it have during anaphase? A) 1 B) 2 C) 4 D) 8 E) 16 Answer: E Share this Share on FacebookTweet on TwitterPlus on Google+