2,3 BPG binds to Hemoglobin in its "Tense" deoxy form but not to the "Relaxed" form/ Why can't it bind to "Relaxed" Hb?

2,3 BPG binds to Hemoglobin in its "Tense" deoxy form but not to the "Relaxed" form/ Why can't it bind to "Relaxed" Hb?



A. the oxygen gets in the way
B. the heme iron is too bulky
C. the central cavity of tetramer is too small
D. it does bind
E. no negative chages


Answer: C


Biology

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