Structure III is a serotonin antagonist. A methyl group has been introducing into analogue IV resulting in increased activity.
What strategy has been used here?
a. Extension
b. Rigidification
c. Conformational blocking
d. Isosteric replacement
Answer: C
Chemistry
- Which of the following objects, all moving at the same speed, will have the highest de Broglies wavelength?
- Which of the following is a correct formation reaction?
- Which of the following gases will be the fastest to diffuse through a room?
- Indicate the gas with the greatest density at 2.3 atm pressure and 22C degrees.
- Which of the following substances is a strong acid?
- Which of the following is a weak base?
- Which of the following is a redox reaction?
- Which of the following will produce a precipitate?
- Which of the following is not ionic?
- Which of the following will be the poorest conductor of electrical current when dissolved in water, assuming equal concentrations?
- Which of the following is a main group metal?
- Which of the following elements is liquid at room temperature?
- Predict the charge that an ion formed from selenium would have.
- Which of the following has the greatest number of electrons?
- An element with the atomic number twelve
- Which of the following is approximately room temperature?
- If the distance between two charged particles is halved, the electrostatic force between them?
- Which represents the largest volume?
- Which of the following is not an Si base unit?
- The process of adding a known amount of solution of known concentration to determine the concentration of another solution is called
- What characterizes a strong acid or base
- Which of these solutions is the most basic
- What is pH
- What is the charge on the hydronium ion
- Which of the following represents a Bronsted-Lowry conjugate acid-base pair