T cells are frequently at fault for causing damage in autoimmune disorders and in transplant rejection. As an immunologist, your dream is to discover a method for decreasing T-cell response to self-antigens. Which of the following would be the BEST target for your research?

T cells are frequently at fault for causing damage in autoimmune disorders and in transplant rejection. As an immunologist, your dream is to discover a method for decreasing T-cell response to self-antigens. Which of the following would be the BEST target for your research?










A. Activated B cells because they make T cell receptor molecules
B. Antibody-mediated apoptosis of dendritic cells
C. CTLA-4 antagonists that block the action of CTLA-4
D. Ligands that block the binding of one co-stimulatory molecule
E. Radiation therapy directed at all T cells















Answer: D


Biology

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