Which of the following is NOT a means of generating diversity in the variable regions of the T cell receptor genes?

Which of the following is NOT a means of generating diversity in the variable regions of the T cell receptor genes?













A. Cleavage at the coding-heptamer RSS junction by RAG-1/2
B. Somatic hypermutation following activation
C. Hairpin cleavage by Artemis to generate P nucleotides
D. Addition of N nucleotides by TdT
E. All of the above generate diversity in the variable regions of the T-cell receptor genes.

















Answer: B