Which of the following mechanisms of mutagenesis via AID activity is possible?
A. The lesion is not repaired prior to replication, resulting in a CG?TA transition.
B. Base excision repair, followed by error-prone DNA polymerase fill-in of the gap created.
C. Mismatch repair, followed by error-prone DNA polymerase fill-in of the gap created.
D. Choices A and B are both possible.
E. All of the above are possible.
Answer: E