Activating end plate acetylcholine receptor channels produces 0 current at 0 mV, but is still able to elicit action potentials in muscle fibers because:

Activating end plate acetylcholine receptor channels produces 0 current at 0 mV, but is still able to elicit action potentials in muscle fibers because:

Activating end plate acetylcholine receptor channels produces 0 current at 0 mV, but is still able to elicit action potentials in muscle fibers because:




  1. the depolarization occurs so quickly that the membrane potential goes far positive to 0 mV and produces an overshooting action potential.
  2. there are enough acetylcholine receptors to propagate the action potential along the length of the muscle fiber.
  3. the receptor is also permeable to calcium, which binds to other channels to elicit action potentials.
  4. depolarization of the membrane to 0 mV is sufficient to bring nearby membrane regions, which contain voltage-gated sodium channels, to threshold.
  5. None of the above; acetylcholine does not elicit muscle action potentials

Answer: 4