Functional neuroimaging studies (by Drevets and Raichle) of subjects with unipolar depression have shown:

Functional neuroimaging studies (by Drevets and Raichle) of subjects with unipolar depression have shown:





  1. decreased blood flow in the amygdala and specific areas in the prefrontal cortex.
  2. no difference in blood flow patterns between depressed and non-depressed subjects.
  3. abnormal blood flow in specific prefrontal cortical areas that continues even after resolution of depressive symptoms.
  4. increased blood flow in the amygdala and specific areas in the prefrontal cortex.
  5. increased blood flow in all limbic structures.

Answer: 4