Which of the following is an adjuvant analgesic/are adjuvant analgesics?

Which of the following is an adjuvant analgesic/are adjuvant analgesics? 

a. Ethanol
b. Tricyclic antidepressants
c. Corticosteroids
d. Local anaesthetics



Answer: B

Which mechanism is relevant to the analgesic action of aspirin?

Which mechanism is relevant to the analgesic action of aspirin?

a. Inhibition of opioid receptors
b. Inhibition of prostaglandin synthesis in the CNS
c. Irreversible inhibition of platelet aggregation
d. Inhibition of prostaglandin synthesis in the periphery



Answer: D

An overdose of opioids may be reversed with:

An overdose of opioids may be reversed with: 

a. methadone
b. pethidine
c. cocaine
d. naloxone.



Answer: D

Which is not considered to be a mechanism of action of opioid analgesics?

Which is not considered to be a mechanism of action of opioid analgesics? 

a. Inhibition of afferent transmission in the dorsal horn
b. Inhibition of pain perception via the limbic system, thalamus, hypothalamus and midbrain
c. Inhibition of substance P release in the dorsal horn
d. Stimulation of sigma receptors in the substantia gelatinosa



Answer: D

Which drug is considered to be a weak opioid, used in mild to moderate pain?

Which drug is considered to be a weak opioid, used in mild to moderate pain? 

a. Paracetamol
b. Codeine
c. Morphine
d. Pethidine



Answer: B

Which route of administration is best for patients with stable chronic pain?

Which route of administration is best for patients with stable chronic pain? 

a. Suppositories (rectal or vaginal)
b. Inhalation
c. Intra-articular
d. Oral sustained-release preparations



Answer: D