What is role of platelets in inflammation?
Answer:
three types of granules: alpha, dense, and lysosome
anucleate
surveillnace role to detect breaches in endothelial surfaces
adhere to subendothelial collagen at site of vascular damage
activated by thrombin or collagen exposure and adhere to exposed subendothelial collagen
release potent inflammatory mediators
platelet derived growth factor induces fibroblast proliferation