Which of the following statements about protein kinase-based signaling is false?
- Serine and threonine kinases are typically activated by second messengers.
- Tyrosine kinases are typically activated by extracellular signals.
- Each protein kinase has just one specific target protein that it phosphorylates.
- The effects of protein kinases can be balanced by protein phosphatases.
- Thousands of protein kinases are expressed in the brain.
Answer: 3