Which of the following statements about the plasticity of synapses in the mammalian CNS is false?

Which of the following statements about the plasticity of synapses in the mammalian CNS is false?





  1. The hallmark of both short-term and long-term synaptic plasticity is that they always increase the strength of synaptic connections.
  2. The efficacy of synapses can be adjusted by modulating the amount of neurotransmitter that is released.
  3. Calcium ions play a central role in at least some forms of synaptic plasticity.
  4. Changes in synaptic efficacy can occur over time scales ranging from milliseconds to years.
  5. A variety of molecular mechanisms are involved in the different forms of synaptic plasticity.

Answer: 1